Densely built the settlement dates back to the Medieval Ages. It spreads amphitheatrically over the port, at an altitude of 260 meters.
With 270 inhabitants today, Chora differs from those of the other Cyclades by its numerous vaulted single-room houses, which occupy a significant area of the settlement. Narrow alleys traverse every corner of the island reaching to the Venetian Castle, the original core and heart of the village. In the center of Chora lie the churches of Agios Nikolaos, Koimisi, Agios Charalambos, Christos Stavros, Agioi Anargyroi and Agios Georgios at the top of the Castle, with Byzantine or post-Byzantine icons. Finds from ancient Anafi are exhibited in the Archaeological Collection.
Pedestrians move freely, since as a traditional settlement Chora is not accessible by wheeled vehicles. Taverns, barbecue, bakery, grocery store and bar, meet the needs of the locals and visitors. As for the accommodation of the second there are several rooms to rent.